Publications

Adipocyte biology from cell identity to disease.

Peer-reviewed research, reviews, and collaborative studies spanning adipogenesis, thermogenesis, metabolism, lipedema, insulin signaling, and related areas.

Current Work

Submitted manuscripts

Manuscripts currently submitted or under review are shown separately from the peer-reviewed publication record.

2026

SubmittedLipedema

Human Lipedema Adipocytes Show Metabolic Inflexibility Despite Preserved Adipogenesis

Poojari A, Dev K, Aguilan J, Hossain MA, Nguyen C, Al Ghadband S, Sidoli S, Rabiee A.

Frontiers in Endocrinology

Submitted · Manuscript ID: 1934404

2026

SubmittedPVAT

Sex-Specific Mechanisms of Perivascular Adipose Tissue (PVAT) Dysfunction in Prediabetes and Diabetes: From Metabolic Crosstalk to Vascular Outcomes

Rabiee A, Rahimian R.

Cells

Submitted · Manuscript ID: cells-4518229

Peer-Reviewed Work

Research articles & reviews

Listed by publication year. An asterisk indicates equal contribution where shown in the CV.

2026

Thermogenesis

Thermogenesis in Adipose Tissue: Adrenergic and Non-Adrenergic Pathways

Hossain MA, Poojari A, Rabiee A.

Cells. 2026 Jan 12;15(2):131.

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2025

Lipedema

Lipedema and Adipose Tissue: Current Understanding, Controversies, and Future Directions

Rabiee A.

Front Cell Dev Biol. 2025 Nov.

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2025

Adipogenesis

A genome-wide, CRISPR-based screen reveals new requirements for translation initiation and ubiquitination in driving adipogenic fate change

Turn RE, Hilgendorf KI, Johnson CT, Han K, Aziz-Zanjani MO, Swails Bollinger S, Domizi P, Cheng R, Rabiee A, Zhu Y, Jiang Z, Asthana A, Demeter J, Svensson KJ, Bassik MC, Jackson PK.

Genes Dev. 2025 Oct 1;39(19-20):1241-1264.

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2025

Metabolism

Adipose Tissue Insulin Resistance: A Key Driver of Metabolic Syndrome Pathogenesis

Rabiee A, Hossain MA, Poojari A.

Biomedicines. 2025 Sep 28;13(10):2376.

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2025

Cardiometabolic

Effects of 17beta-Estradiol Treatment on Metabolic Function and Aortic Relaxation in Castrated Male Rats

Islam R, Razan MR, Poojari A, Rahman MM, Wei H, Alhamadsheh HS, Felmlee M, Rabiee A, Esfandiarei M, Rahimian R.

Int J Mol Sci. 2025 Sep 12;26(18):8885.

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2023

Collaborative

Neuropharmacology of human TERA2.cl.SP12 stem cell-derived neurons in ultra-long-term culture for antiseizure drug discovery

Salmanzadeh H, Poojari A, Rabiee A, Zeitlin BD, Halliwell RF.

Front Neurosci. 2023;17:1182720.

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2022

Cell identity

Early enforcement of cell identity by a functional component of the terminally differentiated state

Bahrami-Nejad Z, Zhang ZB, Tholen S, Sharma S, Rabiee A, Zhao ML, Kraemer FB, Teruel MN.

PLoS Biol. 2022 Dec;20(12):e3001900.

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2022

Lipedema

Lipedema: Insights into Morphology, Pathophysiology, and Challenges

Poojari A, Dev K, Rabiee A.

Biomedicines. 2022 Nov 30;10(12):3081.

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2022

Adipocyte biology

Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy

Tholen S, Patel R*, Agas A*, Kovary KM, Rabiee A, Nicholls HT, Bielczyk-Maczynska E, Yang W, Kraemer FB, Teruel MN.

Cell Rep. 2022 Jun 28;39(13):111018.

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2021

Thermogenesis

Thermogenic Fat: Development, Physiological Function, and Therapeutic Potential

Brandao BB*, Poojari A*, Rabiee A.

Int J Mol Sci. 2021 May 31;22(11):5906.

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2021

Thermogenesis

White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

Rabiee A, Plucinska K, Isidor MSL, Brown EL, Tozzi M, Sidoli S, Petersen PSS, Agueda-Oyarzabal M, Torsetnes SB, Chehabi GN, Lundh M, Altintas A, Barres R, Jensen ON, Gerhart-Hines Z, Emanuelli B.

Mol Metab. 2021 Feb;44:101137.

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2020

Adipogenesis

Insulin-induced serine 22 phosphorylation of retinoid X receptor alpha is dispensable for adipogenesis in brown adipocytes

Ardenkjaer-Larsen JL, Rupar K, Sinke G, Petersen PSS, Villarroel J, Lundh M, Barres R, Rabiee A, Emanuelli B.

Adipocyte. 2020;9(1):142-152.

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2020

Metabolism

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

Brandao BB*, Madsen S*, Rabiee A, Oliverio M, Rocha AL, Ruiz GP, Ferrucci DL, Branquinho JL, Monteiro L, Razolli D, Pinto S, Nielsen TS, Festuccia WT, Knittel TL, Sogaard D, Larsen S, Helge JW, Brandauer J, Velloso LA, Emanuelli B, Kornfeld JW, Pearce EJ, Moraes-Vieira PMM, Kahn CR, Vienberg SG, Zierath JR, Treebak JT, Mori MA.

Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23932-23941.

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2020

Thermogenesis

Beige Fat Maintenance; Toward a Sustained Metabolic Health

Rabiee A.

Front Endocrinol (Lausanne). 2020 Sep 4;11:634.

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2020

Cell identity

Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle

Zhao ML, Rabiee A, Kovary KM, Bahrami-Nejad Z, Taylor B, Teruel MN.

Cell Rep. 2020 Jun 16;31(11):107769.

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2019

Collaborative

Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility

Stowers R, Shcherbina A, Israeli J, Gruber J, Chang J, Nam S, Rabiee A, Teruel M, Snyder M, Kundaje A.

Nat Biomed Eng. 2019 Jul.

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2018

Insulin signaling

Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action

Rabiee A, Kruger M, Ardenkjaer-Larsen J, Kahn CR, Emanuelli B.

Cell Signal. 2018 Jul;47:1-15.

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2017

Proteomics

Nuclear phosphoproteome analysis of 3T3-L1 preadipocyte differentiation reveals system-wide phosphorylation of transcriptional regulators

Rabiee A, Schwammle V, Sidoli S, Dai J, Rogowska-Wrzesinska A, Mandrup S, Jensen ON.

Proteomics. 2017 Mar;17(6).

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2014

Adipogenesis

Transcription factor cooperativity in early adipogenic hotspots and super-enhancers

Siersbaek R*, Rabiee A*, Nielsen R, Sidoli S, Traynor S, Loft A, Poulsen LC, Rogowska-Wrzesinska A, Jensen ON, Mandrup S.

Cell Rep. 2014 Jun 12;7(5):1443-1455.

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2014

Adipogenesis

Molecular architecture of transcription factor hotspots in early adipogenesis

Siersbaek R, Baek S, Rabiee A, Nielsen R, Traynor S, Clark N, Sandelin A, Jensen ON, Sung MH, Hager GL, Mandrup S.

Cell Rep. 2014 Jun 12;7(5):1434-1442.

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2013

Protein biochemistry

How curcumin affords effective protection against amyloid fibrillation in insulin?

Rabiee A, Ebrahim-Habibi A, Ghasemi A, Nemat-Gorgani M.

Food Funct. 2013 Oct;4(10):1474-1480.

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2011

Protein biochemistry

Benzofuranone derivatives as effective small molecules related to insulin amyloid fibrillation: a structure-function study

Rabiee A, Ebrahim-Habibi A, Navidpour L, Morshedi D, Ghasemi A, Sabbaghian M, Nemati-Lay M, Nemat-Gorgani M.

Chem Biol Drug Des. 2011 Oct;78(4):659-666.

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Research Program

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