Dr. Atefeh Rabiee
Principal Investigator

Atefeh Rabiee, PhD

Tenured Associate Professor in the Department of Pharmaceutical Sciences, Thomas J. Long School of Pharmacy, University of the Pacific.

Dr. Rabiee is a cell and molecular biologist whose research centers on adipocyte biology, metabolic flexibility, mitochondrial adaptation, and the mechanisms that connect adipose tissue dysfunction to cardiometabolic disease.

Her scientific path has consistently focused on understanding how fat cells acquire, maintain, and remodel their identity. Her doctoral work examined transcriptional regulation and post-translational control of early adipogenesis. At the University of Copenhagen, she progressed from Postdoctoral Researcher (2014–2018) to Assistant Professor (2018–2020), while also conducting visiting research at Stanford University School of Medicine from 2017–2020 in the laboratories of Dr. Mary Teruel and Dr. Peter K. Jackson.

At the University of the Pacific, she established the Rabiee Laboratory to investigate disease-specific adipocyte biology, with particular emphasis on lipedema, mitochondrial dysfunction, adipocyte metabolic inflexibility, and adipose tissue communication with vascular and tumor microenvironments.

Scientific Path

From adipogenesis to metabolic disease.

A research trajectory spanning molecular adipogenesis, insulin signaling, thermogenesis, and translational adipose biology.

2025–Present

University of the Pacific

Associate Professor

Department of Pharmaceutical Sciences, Thomas J. Long School of Pharmacy.

2020–2025

University of the Pacific

Assistant Professor

Established an independent research program focused on adipocyte biology, lipedema, and metabolic disease.

2018–2020

University of Copenhagen

Assistant Professor

Continued research in adipose tissue biology, insulin signaling, cold-induced browning, thermogenesis, and metabolic regulation in diabetes.

2017–2020

Stanford University School of Medicine

Visiting Researcher

Research in the Departments of Microbiology & Immunology and Chemical and Systems Biology, including work in the laboratories of Mary Teruel and Peter K. Jackson.

2014–2018

University of Copenhagen

Postdoctoral Researcher

Studied insulin signaling, cold-induced adipose browning and thermogenesis, and metabolic regulation in diabetes.

2010–2014

University of Southern Denmark

PhD in Biochemistry and Molecular Biology

Dissertation: investigation of transcription factors and proteins involved in early adipogenesis using combined proteomic-genomic approaches.

2006–2009

Azad University, Science and Research Branch

MSc in Biochemistry

Studied insulin protein modification, structure, and aggregation in vitro.

Research Vision

Adipocytes are not passive storage cells.

The Rabiee Laboratory views adipocytes as dynamic cells that integrate nutrient signals, mitochondrial function, lipid handling, endocrine communication, and tissue-level adaptation. The lab's current work asks why this adaptability fails in disease and whether dysfunctional adipocytes can be therapeutically reprogrammed.

Current research spans lipedema, mitochondrial and thermogenic biology, perivascular adipose tissue, and adipocyte interactions with disease microenvironments.

Selected Highlights

Awards, scholarship & mentorship

$600K

Novo Nordisk Foundation / Stanford Bio-X Visiting Research Scholar Fellowship

Supported interdisciplinary research at Stanford University.

$250K

Collaborative Lipedema Foundation Award

Supported a multi-year research program in lipedema biology.

2024

Graduate Advisor of the Year

University of the Pacific.

2024

Pre-Tenured Research Award

Pacific Office of Research and Sponsored Programs.

Selected Research

Representative contributions

2026

Thermogenesis in Adipose Tissue: Adrenergic and Non-Adrenergic Pathways

Hossain MA, Poojari A, Rabiee A. Cells.

2025

Lipedema and Adipose Tissue: Current Understanding, Controversies, and Future Directions

Rabiee A. Frontiers in Cell and Developmental Biology.

2021

White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment

Rabiee A, et al. Molecular Metabolism.

2018

Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action

Rabiee A, et al. Cellular Signalling.

2017

Nuclear phosphoproteome analysis of 3T3-L1 preadipocyte differentiation

Rabiee A, et al. Proteomics.

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